Product ID:ETHIDIUM BROMIDE MOLECULAR BIOLOGY REAGENT, E7637
MSDS Date:01/01/1999
FSC:6550
NIIN:00N092546
Status Code:A
MSDS Number: CJSTK

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

PHENANTHRIDINIUM, 3,8-DIAMINO-5-ETHYL-6-PHENYL-, BROMIDE

CAS: 1239-45-8

RTECS: SF7950000

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INHALATION,
INGESTION OR SKIN ABSORPTION. CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY
TRACT. CHRONIC EFFECTS: MAY ALTER GE NETIC MATERIAL. TO THE BEST OF
MANUFACTURER'S KNOWLEDGE, THE CHEMICAL, PHYSICAL AND TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THROUGHLY INVESTIGATED. ALSO, SEE
TOXICOLOGICAL INFORMATION.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IN CASE OF CONTACT,
IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
INHALATI ON: REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGESTION:
WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A
PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE.

Extinguishing Media:WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA AND WASH SPILL SI TE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:KEEP TIGHTLY CLOSED. STORE IN A COOL,
DRY PLACE.
Other Precautions:DO NOT BREATHE DUST. DO NOT GET IN EYES, ON SKIN, ON
CLOTHING. WASH THOROUGHLY AFTER HANDLING. IRRITANT. MUTAGEN.

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR OTHER PROTECTIVE CLOTHING.
Supplemental Safety and Health

Melt/Freeze Pt:>260.C, 500.F
M.P/F.P Text:260-262C (DEC)
Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Hazardous Decomposition Products:TOXIC FUMES OF CARBON MONOXIDE, CARBON
DIOXIDE. NITROGEN OXIDES. HYDROGEN BROMIDE GAS.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:RTECS #: SF7950000 PHENANTHRIDINIUM,
3,8-DIAMINO-5-ETHYL-6-PHENYL-, BROMIDE - TOXICITY DATA: SCU-MUS
LD50: 110 MG/KG ATMPA2 46, 285, 1952. TARGET ORGAN DATA -
TUMORIGENIC (ACTIVE AS ANTI-CANCER AGENT) . ONLY SELECTED REGISTRY
OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENED
HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE. OTHER INFO: POSITIVE: E COLI POLA
WITHOUT S9; HISTIDINE REVERSION-AMES TEST. EPA GENETOX PROGRAM
1988, NEGATIVE: CELL TRANSFORM. -SA7/SHE; SPERM MORPHOLOGY-MOUSE.
EPA GENETOX P ROGRAM 1988, NEGATIVE: S CEREVISIAE GENE CONVERSION;
S CEREVISIAE-HOMOZYGOSIS. EPA GENETOX PROGRAM 1988, NEGATIVE: S
CEREVISIAE-REVERSION. EPA GENETOX PROGRAM 1988, INCONCLUSIVE:
CYTOGENETICS-MALE GER M CELL. EPA GENETOX PROGRAM 1988, POSITIVE:
CHO GENE MUTATION. NTP CARCINOGENESIS STUDIES; SELECTED, OCTOBER
1977.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFO - TOXIC. R 46 MAY CAUSE
HERITABLE GENETIC DAMAGE. R 36/37/38 IRRITATING TO EYES,
RESPIRATORY SYSTEM AND SKIN. S 45 IN CASE OF ACCIDENT OF IF YOU
FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIAT ELY (SHOW THE LABEL WHERE
POSSIBLE). S 26 IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY
WITH PLENTY OF WATER AND SEEK MEDICAL ADVICE. S 22 DO NOT BREATHE
DUST. S 23 DO NOT BREATHE FUMES.